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MicroRNA-146a Regulates Human Foetal Femur Derived Skeletal Stem Cell Differentiation by Down-Regulating SMAD2 and SMAD3

MicroRNAs (miRs) play a pivotal role in a variety of biological processes including stem cell differentiation and function. Human foetal femur derived skeletal stem cells (SSCs) display enhanced proliferation and multipotential capacity indicating excellent potential as candidates for tissue enginee...

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Detalhes bibliográficos
Main Authors: Cheung, Kelvin S. C., Sposito, Nunzia, Stumpf, Patrick S., Wilson, David I., Sanchez-Elsner, Tilman, Oreffo, Richard O. C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4043645/
https://ncbi.nlm.nih.gov/pubmed/24892945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098063
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