MicroRNA-146a Regulates Human Foetal Femur Derived Skeletal Stem Cell Differentiation by Down-Regulating SMAD2 and SMAD3

MicroRNAs (miRs) play a pivotal role in a variety of biological processes including stem cell differentiation and function. Human foetal femur derived skeletal stem cells (SSCs) display enhanced proliferation and multipotential capacity indicating excellent potential as candidates for tissue enginee...

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Autores principales: Cheung, Kelvin S. C., Sposito, Nunzia, Stumpf, Patrick S., Wilson, David I., Sanchez-Elsner, Tilman, Oreffo, Richard O. C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4043645/
https://ncbi.nlm.nih.gov/pubmed/24892945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098063
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