Regionally-derived cell populations and skeletal stem cells from human foetal femora exhibit specific osteochondral and multi-lineage differentiation capacity in vitro and ex vivo

BACKGROUND: Adult skeletal stem cells (SSCs) often exhibit limited in vitro expansion with undesirable phenotypic changes and loss of differentiation capacity. Foetal tissues offer an alternative cell source, providing SSCs which exhibit desirable differentiation capacity over prolonged periods, ide...

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Dettagli Bibliografici
Pubblicato in:Stem Cell Res Ther
Autori principali: Gothard, David, Cheung, Kelvin, Kanczler, Janos M., Wilson, David I., Oreffo, Richard O. C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4683700/
https://ncbi.nlm.nih.gov/pubmed/26684339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-015-0247-2
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