Regionally-derived cell populations and skeletal stem cells from human foetal femora exhibit specific osteochondral and multi-lineage differentiation capacity in vitro and ex vivo

BACKGROUND: Adult skeletal stem cells (SSCs) often exhibit limited in vitro expansion with undesirable phenotypic changes and loss of differentiation capacity. Foetal tissues offer an alternative cell source, providing SSCs which exhibit desirable differentiation capacity over prolonged periods, ide...

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Veröffentlicht in:Stem Cell Res Ther
Hauptverfasser: Gothard, David, Cheung, Kelvin, Kanczler, Janos M., Wilson, David I., Oreffo, Richard O. C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4683700/
https://ncbi.nlm.nih.gov/pubmed/26684339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-015-0247-2
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