Regionally-derived cell populations and skeletal stem cells from human foetal femora exhibit specific osteochondral and multi-lineage differentiation capacity in vitro and ex vivo

BACKGROUND: Adult skeletal stem cells (SSCs) often exhibit limited in vitro expansion with undesirable phenotypic changes and loss of differentiation capacity. Foetal tissues offer an alternative cell source, providing SSCs which exhibit desirable differentiation capacity over prolonged periods, ide...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Gothard, David, Cheung, Kelvin, Kanczler, Janos M., Wilson, David I., Oreffo, Richard O. C.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4683700/
https://ncbi.nlm.nih.gov/pubmed/26684339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-015-0247-2
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