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The Effects of 1α, 25-dihydroxyvitamin D(3) and Transforming Growth Factor-β3 on Bone Development in an Ex Vivo Organotypic Culture System of Embryonic Chick Femora

Transforming growth factor-beta3 (TGF-β3) and 1α,25-dihydroxyvitamin D(3) (1α,25 (OH) (2)D(3)) are essential factors in chondrogenesis and osteogenesis respectively. These factors also play a fundamental role in the developmental processes and the maintenance of skeletal integrity, but their respect...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Smith, Emma L., Rashidi, Hassan, Kanczler, Janos M., Shakesheff, Kevin M., Oreffo, Richard O. C.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4383569/
https://ncbi.nlm.nih.gov/pubmed/25835745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121653
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