Identification of T. gondii Myosin Light Chain-1 as a Direct Target of TachypleginA-2, a Small-Molecule Inhibitor of Parasite Motility and Invasion

Motility of the protozoan parasite Toxoplasma gondii plays an important role in the parasite’s life cycle and virulence within animal and human hosts. Motility is driven by a myosin motor complex that is highly conserved across the Phylum Apicomplexa. Two key components of this complex are the class...

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Detalhes bibliográficos
Main Authors: Leung, Jacqueline M., Tran, Fanny, Pathak, Ravindra B., Poupart, Séverine, Heaslip, Aoife T., Ballif, Bryan A., Westwood, Nicholas J., Ward, Gary E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4043638/
https://ncbi.nlm.nih.gov/pubmed/24892871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098056
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