A Small-Molecule Inhibitor of T. gondii Motility Induces the Posttranslational Modification of Myosin Light Chain-1 and Inhibits Myosin Motor Activity

Toxoplasma gondii is an obligate intracellular parasite that enters cells by a process of active penetration. Host cell penetration and parasite motility are driven by a myosin motor complex consisting of four known proteins: TgMyoA, an unconventional Class XIV myosin; TgMLC1, a myosin light chain;...

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Detalhes bibliográficos
Main Authors: Heaslip, Aoife T., Leung, Jacqueline M., Carey, Kimberly L., Catti, Federica, Warshaw, David M., Westwood, Nicholas J., Ballif, Bryan A., Ward, Gary E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2800044/
https://ncbi.nlm.nih.gov/pubmed/20084115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000720
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