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Identification of T. gondii Myosin Light Chain-1 as a Direct Target of TachypleginA-2, a Small-Molecule Inhibitor of Parasite Motility and Invasion

Motility of the protozoan parasite Toxoplasma gondii plays an important role in the parasite’s life cycle and virulence within animal and human hosts. Motility is driven by a myosin motor complex that is highly conserved across the Phylum Apicomplexa. Two key components of this complex are the class...

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Bibliografske podrobnosti
Main Authors: Leung, Jacqueline M., Tran, Fanny, Pathak, Ravindra B., Poupart, Séverine, Heaslip, Aoife T., Ballif, Bryan A., Westwood, Nicholas J., Ward, Gary E.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4043638/
https://ncbi.nlm.nih.gov/pubmed/24892871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098056
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