A randomized controlled trial of inhaled corticosteroids (ICS) on markers of epithelial–mesenchymal transition (EMT) in large airway samples in COPD: an exploratory proof of concept study

BACKGROUND: We recently reported that epithelial–mesenchymal transition (EMT) is active in the airways in chronic obstructive pulmonary disease (COPD), suggesting presence of an active profibrotic and promalignant stroma. With no data available on potential treatment effects, we undertook a blinded...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sohal, Sukhwinder Singh, Soltani, Amir, Reid, David, Ward, Chris, Wills, Karen E, Muller, H Konrad, Walters, Eugene Haydn
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Dove Medical Press 2014
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4043431/
https://ncbi.nlm.nih.gov/pubmed/24920891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/COPD.S63911
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