A randomized controlled trial of inhaled corticosteroids (ICS) on markers of epithelial–mesenchymal transition (EMT) in large airway samples in COPD: an exploratory proof of concept study

BACKGROUND: We recently reported that epithelial–mesenchymal transition (EMT) is active in the airways in chronic obstructive pulmonary disease (COPD), suggesting presence of an active profibrotic and promalignant stroma. With no data available on potential treatment effects, we undertook a blinded...

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Autori principali: Sohal, Sukhwinder Singh, Soltani, Amir, Reid, David, Ward, Chris, Wills, Karen E, Muller, H Konrad, Walters, Eugene Haydn
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2014
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4043431/
https://ncbi.nlm.nih.gov/pubmed/24920891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/COPD.S63911
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