A randomized controlled trial of inhaled corticosteroids (ICS) on markers of epithelial–mesenchymal transition (EMT) in large airway samples in COPD: an exploratory proof of concept study

BACKGROUND: We recently reported that epithelial–mesenchymal transition (EMT) is active in the airways in chronic obstructive pulmonary disease (COPD), suggesting presence of an active profibrotic and promalignant stroma. With no data available on potential treatment effects, we undertook a blinded...

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Detalhes bibliográficos
Main Authors: Sohal, Sukhwinder Singh, Soltani, Amir, Reid, David, Ward, Chris, Wills, Karen E, Muller, H Konrad, Walters, Eugene Haydn
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2014
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4043431/
https://ncbi.nlm.nih.gov/pubmed/24920891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/COPD.S63911
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