A randomized controlled trial of inhaled corticosteroids (ICS) on markers of epithelial–mesenchymal transition (EMT) in large airway samples in COPD: an exploratory proof of concept study

BACKGROUND: We recently reported that epithelial–mesenchymal transition (EMT) is active in the airways in chronic obstructive pulmonary disease (COPD), suggesting presence of an active profibrotic and promalignant stroma. With no data available on potential treatment effects, we undertook a blinded...

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Bibliografske podrobnosti
Main Authors: Sohal, Sukhwinder Singh, Soltani, Amir, Reid, David, Ward, Chris, Wills, Karen E, Muller, H Konrad, Walters, Eugene Haydn
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2014
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4043431/
https://ncbi.nlm.nih.gov/pubmed/24920891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/COPD.S63911
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