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Histone Deacetylase Inhibitors: A Chemical Genetics Approach to Understanding Cellular Functions
There are eleven zinc dependent histone deacetylases (HDAC) in humans which have histones and many non-histone substrates. The substrates of these enzymes include proteins that have a role in regulation of gene expression, cell proliferation, cell migration, cell death, immune pathways and angiogene...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4043339/ https://ncbi.nlm.nih.gov/pubmed/20594930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2010.05.008 |
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