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Histone Deacetylase Inhibitors: A Chemical Genetics Approach to Understanding Cellular Functions

There are eleven zinc dependent histone deacetylases (HDAC) in humans which have histones and many non-histone substrates. The substrates of these enzymes include proteins that have a role in regulation of gene expression, cell proliferation, cell migration, cell death, immune pathways and angiogene...

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Hlavní autor: Marks, Paul A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4043339/
https://ncbi.nlm.nih.gov/pubmed/20594930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2010.05.008
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