Multiple sweet receptors and transduction pathways revealed in knockout mice by temperature dependence and gurmarin sensitivity

Sweet taste transduction involves taste receptor type 1, member 2 (T1R2), taste receptor type 1, member 3 (T1R3), gustducin, and TRPM5. Because knockout (KO) mice lacking T1R3, gustducin's Gα subunit (Gαgust), or TRPM5 exhibited greatly reduced, but not abolished responses of the chorda tympani...

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Autores principales: Ohkuri, Tadahiro, Yasumatsu, Keiko, Horio, Nao, Jyotaki, Masafumi, Margolskee, Robert F., Ninomiya, Yuzo
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2009
Materias:
Receptors and Signaling Pathways
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4043322/
https://ncbi.nlm.nih.gov/pubmed/19211717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.91018.2008
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