Breast cancer resistance protein (ABCG2) and drug disposition: intestinal expression, polymorphisms and sulfasalazine as an in vivo probe

Breast cancer resistance protein (BCRP) is an efflux transporter expressed in tissues that act as barriers to drug entry. Given that single nucleotide polymorphisms (SNPs) in the ABCG2 gene encoding BCRP are common, the possibility exists that these genetic variants may be a determinant of interindi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Urquhart, Bradley L., Ware, Joseph A., Tirona, Rommel G., Ho, Richard H., Leake, Brenda F., Schwarz, Ute I., Zaher, Hani, Palandra, Joe, Gregor, Jamie C., Dresser, George K., Kim, Richard B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4043148/
https://ncbi.nlm.nih.gov/pubmed/18408567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e3282f974dc
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