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Incomplete pneumolysin oligomers form membrane pores

Pneumolysin is a member of the cholesterol-dependent cytolysin (CDC) family of pore-forming proteins that are produced as water-soluble monomers or dimers, bind to target membranes and oligomerize into large ring-shaped assemblies comprising approximately 40 subunits and approximately 30 nm across....

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Detalhes bibliográficos
Main Authors: Sonnen, Andreas F.-P., Plitzko, Jürgen M., Gilbert, Robert J. C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4043118/
https://ncbi.nlm.nih.gov/pubmed/24759615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.140044
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