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Regulatory interplay between TFIID’s conformational transitions and its modular interaction with core promoter DNA

Recent structural and biochemical studies of human TFIID have significantly increased our understanding of the mechanisms underlying the recruitment of TFIID to promoter DNA and its role in transcription initiation. Structural studies using cryo-EM revealed that modular interactions underlie TFIID’s...

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Détails bibliographiques
Auteurs principaux: Cianfrocco, Michael A, Nogales, Eva
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4042585/
https://ncbi.nlm.nih.gov/pubmed/23863784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/trns.25291
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