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Tetraphenylporphyrin derivative specifically blocks members of the voltage-gated potassium channel subfamily Kv1
Tetraphenylporphyrin derivatives represent a promising class of high-affinity ligands for voltage-gated potassium (Kv) channels. Herein, we investigated the mode of Kv channel block of one tetraphenylporphyrin derivative, por3, using electrophysiological methods, structure-based mutagenesis, and sol...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Landes Bioscience
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4042482/ https://ncbi.nlm.nih.gov/pubmed/24722265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.25848 |
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