Physiologically Based Pharmacokinetic Modeling Framework for Quantitative Prediction of an Herb–Drug Interaction

Herb–drug interaction predictions remain challenging. Physiologically based pharmacokinetic (PBPK) modeling was used to improve prediction accuracy of potential herb–drug interactions using the semipurified milk thistle preparation, silibinin, as an exemplar herbal product. Interactions between sili...

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Detaylı Bibliyografya
Asıl Yazarlar: Brantley, S J, Gufford, B T, Dua, R, Fediuk, D J, Graf, T N, Scarlett, Y V, Frederick, K S, Fisher, M B, Oberlies, N H, Paine, M F
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2014
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4042458/
https://ncbi.nlm.nih.gov/pubmed/24670388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/psp.2013.69
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