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Vasodilator responses to acetylcholine are not mediated by the activation of soluble guanylate cyclase or TRPV4 channels in the rat

The effects of 1H-[1,2,4]-oxadizaolo[4,3-]quinoxaline-1-one (ODQ), an inhibitor of the activation of soluble guanylate cyclase (sGC) on responses to NO donors acetylcholine (ACh) and bradykinin (BK) were investigated in the pulmonary and systemic vascular beds of the rat. In these studies the admini...

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Detalhes bibliográficos
Main Authors: Pankey, Edward A., Kassan, Modar, Choi, Soo-Kyoung, Matrougui, Khalid, Nossaman, Bobby D., Hyman, Albert L., Kadowitz, Philip J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4042198/
https://ncbi.nlm.nih.gov/pubmed/24658016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00978.2013
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