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PACAP-induced ERK activation in HEK cells expressing PAC1 receptors involves both receptor internalization and PKC signaling

The pituitary adenylate cyclase-activating polypeptide (PACAP)-selective PAC1 receptor (Adcyap1r1) is a G protein-coupled receptor (GPCR) that activates adenylyl cyclase and PLC. Similar to many other GPCRs, our previous studies showed that the PAC1 receptor is internalized after ligand binding to f...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: May, Victor, Buttolph, Thomas R., Girard, Beatrice M., Clason, Todd A., Parsons, Rodney L.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Physiological Society 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4042093/
https://ncbi.nlm.nih.gov/pubmed/24696141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00001.2014
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