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Ligand-Independent Canonical Wnt Activity in Canine Mammary Tumor Cell Lines Associated with Aberrant LEF1 Expression

Pet dogs very frequently develop spontaneous mammary tumors and have been suggested as a good model organism for breast cancer research. In order to obtain an insight into underlying signaling mechanisms during canine mammary tumorigenesis, in this study we assessed the incidence and the mechanism o...

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Bibliografiske detaljer
Main Authors: Gracanin, Ana, Timmermans-Sprang, Elpetra P. M., van Wolferen, Monique E., Rao, Nagesha A. S., Grizelj, Juraj, Vince, Silvijo, Hellmen, Eva, Mol, Jan A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041801/
https://ncbi.nlm.nih.gov/pubmed/24887235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098698
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