Ligand-Independent Canonical Wnt Activity in Canine Mammary Tumor Cell Lines Associated with Aberrant LEF1 Expression

Pet dogs very frequently develop spontaneous mammary tumors and have been suggested as a good model organism for breast cancer research. In order to obtain an insight into underlying signaling mechanisms during canine mammary tumorigenesis, in this study we assessed the incidence and the mechanism o...

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Bibliographic Details
Main Authors: Gracanin, Ana, Timmermans-Sprang, Elpetra P. M., van Wolferen, Monique E., Rao, Nagesha A. S., Grizelj, Juraj, Vince, Silvijo, Hellmen, Eva, Mol, Jan A.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041801/
https://ncbi.nlm.nih.gov/pubmed/24887235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098698
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