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P-cadherin mutations are associated with high basal Wnt activity and stemness in canine mammary tumor cell lines
Purpose: To find underlying mutations causing highly-activated Wnt activity in mammary tumor cell lines associated with rounded morphology indicative of stemness/EMT. Methods: Stemness of high Wnt cell lines was confirmed using qPCR on selected genes and microRNA profiling, followed by whole-exome s...
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| Publié dans: | Oncotarget |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Impact Journals LLC
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6508207/ https://ncbi.nlm.nih.gov/pubmed/31105876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26873 |
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