A Non-Canonical NRPS Is Involved in the Synthesis of Fungisporin and Related Hydrophobic Cyclic Tetrapeptides in Penicillium chrysogenum

The filamentous fungus Penicillium chrysogenum harbors an astonishing variety of nonribosomal peptide synthetase genes, which encode proteins known to produce complex bioactive metabolites from simple building blocks. Here we report a novel non-canonical tetra-modular nonribosomal peptide synthetase...

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Bibliografski detalji
Glavni autori: Ali, Hazrat, Ries, Marco I., Lankhorst, Peter P., van der Hoeven, Rob A. M., Schouten, Olaf L., Noga, Marek, Hankemeier, Thomas, van Peij, Noël N. M. E., Bovenberg, Roel A. L., Vreeken, Rob J., Driessen, Arnold J. M.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041764/
https://ncbi.nlm.nih.gov/pubmed/24887561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098212
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