Synthesis of sFlt-1 by platelet-monocyte aggregates contributes to the pathogenesis of preeclampsia

OBJECTIVE: Soluble fms-like tyrosine kinase (sFlt-1) is an important mediator in the pathogenesis of preeclampsia. We sought to determine if platelet-monocyte aggregates (PMAs) produced sFlt-1 and if PMAs contributed to sFlt-1 production in preeclampsia. STUDY DESIGN: Case-control study of sFlt-1 re...

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Hlavní autoři: Major, Heather D., Cambell, Robert A., Silver, Robert M., Branch, D. Ware, Weyrich, Andrew S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041388/
https://ncbi.nlm.nih.gov/pubmed/24440566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajog.2014.01.024
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