11β-Hydroxysteroid dehydrogenase inhibition improves cognitive function in healthy elderly men and type 2 diabetics

In aging humans and rodents, inter-individual differences in cognitive function have been ascribed to variations in long-term glucocorticoid exposure. 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) regenerates the active glucocorticoid cortisol from circulating inert cortisone, thus amplifying i...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Sandeep, Thekkepat C., Yau, Joyce L. W., MacLullich, Alasdair M. J., Noble, June, Deary, Ian J., Walker, Brian R., Seckl, Jonathan R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2004
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC404114/
https://ncbi.nlm.nih.gov/pubmed/15071189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0306996101
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia