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RNA interference microarrays: High-throughput loss-of-function genetics in mammalian cells

RNA interference (RNAi) is a biological process in which a doubles-tranded RNA directs the silencing of target genes in a sequence-specific manner. Exogenously delivered or endogenously encoded double-stranded RNAs can enter the RNAi pathway and guide the suppression of transgenes and cellular genes...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Silva, Jose M., Mizuno, Hana, Brady, Amy, Lucito, Robert, Hannon, Gregory J.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC404082/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15084744/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0400165101
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