A lentiviral microRNA-based system for single-copy polymerase II-regulated RNA interference in mammalian cells

The advent of RNA interference has led to the ability to interfere with gene expression and greatly expanded our ability to perform genetic screens in mammalian cells. The expression of short hairpin RNA (shRNA) from polymerase III promoters can be encoded in transgenes and used to produce small int...

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Detaylı Bibliyografya
Asıl Yazarlar: Stegmeier, Frank, Hu, Guang, Rickles, Richard J., Hannon, Gregory J., Elledge, Stephen J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2005
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1196357/
https://ncbi.nlm.nih.gov/pubmed/16141338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506306102
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