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RNA interference microarrays: High-throughput loss-of-function genetics in mammalian cells

RNA interference (RNAi) is a biological process in which a doubles-tranded RNA directs the silencing of target genes in a sequence-specific manner. Exogenously delivered or endogenously encoded double-stranded RNAs can enter the RNAi pathway and guide the suppression of transgenes and cellular genes...

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Detalhes bibliográficos
Main Authors: Silva, Jose M., Mizuno, Hana, Brady, Amy, Lucito, Robert, Hannon, Gregory J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC404082/
https://ncbi.nlm.nih.gov/pubmed/15084744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400165101
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