Zinc depletion regulates the processing and secretion of IL-1β

Sterile inflammation contributes to many common and serious human diseases. The pro-inflammatory cytokine interleukin-1β (IL-1β) drives sterile inflammatory responses and is thus a very attractive therapeutic target. Activation of IL-1β in sterile diseases commonly requires an intracellular multi-pr...

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Autors principals: Summersgill, H, England, H, Lopez-Castejon, G, Lawrence, C B, Luheshi, N M, Pahle, J, Mendes, P, Brough, D
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040701/
https://ncbi.nlm.nih.gov/pubmed/24481454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.547
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