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Human Topoisomerase IIα: Targeting to Subchromosomal Sites of Activity during Interphase and Mitosis

Mammalian topoisomerase IIα (topo IIα) plays a vital role in the removal of topological complexities left on DNA during S phase. Here, we developed a new assay to selectively identify sites of catalytic activity of topo IIα with subcellular resolution. We show that topo IIα activity concentrates at...

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Udgivet i:Mol Biol Cell
Principais autores: Agostinho, Marta, Rino, José, Braga, José, Ferreira, Fernando, Steffensen, Soren, Ferreira, João
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Cell Biology 2004
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Articles
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC404031/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14978217/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E03-08-0558
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