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Human Topoisomerase IIα: Targeting to Subchromosomal Sites of Activity during Interphase and Mitosis
Mammalian topoisomerase IIα (topo IIα) plays a vital role in the removal of topological complexities left on DNA during S phase. Here, we developed a new assay to selectively identify sites of catalytic activity of topo IIα with subcellular resolution. We show that topo IIα activity concentrates at...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC404031/ https://ncbi.nlm.nih.gov/pubmed/14978217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-08-0558 |
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