Human Topoisomerase IIα: Targeting to Subchromosomal Sites of Activity during Interphase and Mitosis

Mammalian topoisomerase IIα (topo IIα) plays a vital role in the removal of topological complexities left on DNA during S phase. Here, we developed a new assay to selectively identify sites of catalytic activity of topo IIα with subcellular resolution. We show that topo IIα activity concentrates at...

Full description

Saved in:
Bibliographic Details
Main Authors: Agostinho, Marta, Rino, José, Braga, José, Ferreira, Fernando, Steffensen, Soren, Ferreira, João
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2004
Subjects:
Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC404031/
https://ncbi.nlm.nih.gov/pubmed/14978217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-08-0558
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items