Lack of evidence for association of meiotic nondisjunction with particular DNA haplotypes on chromosome 21.

The hypothesis of a predisposition to meiotic nondisjunction for chromosome 21 carrying a specific molecular haplotype has been tested. The haplotype in question is defined by the restriction fragment length polymorphisms for the D21S1/D21S11 loci. Our results obtained on a sample of Northern Italia...

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Bibliographic Details
Main Authors: Sacchi, N, Gusella, J F, Perroni, L, Bricarelli, F D, Papas, T S
Format: Artigo
Language:Inglês
Published: 1988
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC280522/
https://ncbi.nlm.nih.gov/pubmed/2898783
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