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Lack of evidence for association of meiotic nondisjunction with particular DNA haplotypes on chromosome 21.

The hypothesis of a predisposition to meiotic nondisjunction for chromosome 21 carrying a specific molecular haplotype has been tested. The haplotype in question is defined by the restriction fragment length polymorphisms for the D21S1/D21S11 loci. Our results obtained on a sample of Northern Italia...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Sacchi, N, Gusella, J F, Perroni, L, Bricarelli, F D, Papas, T S
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280522/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2898783/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.13.4794
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