MYC interacts with the human STAGA coactivator complex via multivalent contacts with the GCN5 and TRRAP subunits

MYC is an oncogenic DNA-binding transcription activator of many genes and is often upregulated in human cancers. MYC has an N-terminal transcription activation domain (TAD) that is also required for cell transformation. Various MYC TAD-interacting coactivators have been identified, including the tra...

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Hlavní autoři: Zhang, Na, Ichikawa, Wataru, Faiola, Francesco, Lo, Szu-Ying, Liu, Xiaohui, Martinez, Ernest
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4039629/
https://ncbi.nlm.nih.gov/pubmed/24705139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2014.03.017
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