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MYC interacts with the human STAGA coactivator complex via multivalent contacts with the GCN5 and TRRAP subunits
MYC is an oncogenic DNA-binding transcription activator of many genes and is often upregulated in human cancers. MYC has an N-terminal transcription activation domain (TAD) that is also required for cell transformation. Various MYC TAD-interacting coactivators have been identified, including the tra...
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| Glavni autori: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2014
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4039629/ https://ncbi.nlm.nih.gov/pubmed/24705139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2014.03.017 |
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