Dual Regulation of c-Myc by p300 via Acetylation-Dependent Control of Myc Protein Turnover and Coactivation of Myc-Induced Transcription

The c-Myc oncoprotein (Myc) controls cell fate by regulating gene transcription in association with a DNA-binding partner, Max. While Max lacks a transcription regulatory domain, the N terminus of Myc contains a transcription activation domain (TAD) that recruits cofactor complexes containing the hi...

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Detalhes bibliográficos
Main Authors: Faiola, Francesco, Liu, Xiaohui, Lo, Szuying, Pan, Songqin, Zhang, Kangling, Lymar, Elena, Farina, Anthony, Martinez, Ernest
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2005
Assuntos:
Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1291249/
https://ncbi.nlm.nih.gov/pubmed/16287840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.23.10220-10234.2005
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