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Decorin differentially modulates the activity of insulin receptor isoform A ligands
The proteoglycan decorin, a key component of the tumor stroma, regulates the action of several tyrosine-kinase receptors, including the EGFR, Met and the IGF-IR. Notably, the action of decorin in regulating the IGF-I system differs between normal and transformed cells. In normal cells, decorin binds...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4039619/ https://ncbi.nlm.nih.gov/pubmed/24389353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2013.12.010 |
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