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Evidence of the Innate Antiviral and Neuroprotective Properties of Progranulin

BACKGROUND: Compelling data exist that show that normal levels of progranulin (PGRN) are required for successful CNS aging. PGRN production is also modulated by inflammation and infection, but no data are available on the production and role of PGRN during CNS HIV infection. METHODS: To determine th...

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Bibliographic Details
Main Authors: Suh, Hyeon-Sook, Lo, Yungtai, Choi, Namjong, Letendre, Scott, Lee, Sunhee C.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4039467/
https://ncbi.nlm.nih.gov/pubmed/24878635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098184
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