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Histone deacetylase inhibitors suppress the expression of inflammatory and innate immune response genes in human microglia and astrocytes

Histone deacetylase inhibitors (HDACi) have been proposed as therapies for certain cancers and as an anti-reservoir therapy for HIV+ individuals with HAART, yet, their roles in glial inflammatory and innate antiviral gene expression have not been defined. In this study, we examined the effects of tw...

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Detalhes bibliográficos
Main Authors: Suh, Hyeon-Sook, Choi, Shinyeop, Khattar, Pallavi, Choi, Namjong, Lee, Sunhee C
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115474/
https://ncbi.nlm.nih.gov/pubmed/20157787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-010-9192-0
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