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TLR3 and TLR4 are innate antiviral immune receptors in human microglia: role of IRF3 in modulating antiviral and inflammatory response in the CNS

In the CNS, microglia are the primary targets of HIV infection. In this study, we investigated the effect of activation of the innate antiviral receptors TLR3 and TLR4 on HIV infection of primary human microglia, as well as microglial cell signaling and gene expression. Ligands for both TLR3 and TLR...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Suh, Hyeon-Sook, Zhao, Meng-Liang, Choi, Namjong, Belbin, Thomas J., Brosnan, Celia F., Lee, Sunhee C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752833/
https://ncbi.nlm.nih.gov/pubmed/19646728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.07.001
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