Nucleotide degradation and ribose salvage in yeast

Nucleotide degradation is a universal metabolic capability. Here we combine metabolomics, genetics and biochemistry to characterize the yeast pathway. Nutrient starvation, via PKA, AMPK/SNF1, and TOR, triggers autophagic breakdown of ribosomes into nucleotides. A protein not previously associated wi...

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Bibliografiske detaljer
Main Authors: Xu, Yi-Fan, Létisse, Fabien, Absalan, Farnaz, Lu, Wenyun, Kuznetsova, Ekaterina, Brown, Greg, Caudy, Amy A, Yakunin, Alexander F, Broach, James R, Rabinowitz, Joshua D
Format: Artigo
Sprog:Inglês
Udgivet: European Molecular Biology Organization 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4039369/
https://ncbi.nlm.nih.gov/pubmed/23670538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2013.21
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