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CaMKII and MEK1/2 inhibition time-dependently modify inflammatory signaling in rat cerebral arteries during organ culture

BACKGROUND: Cerebral ischemia induces transcriptional upregulation of inflammatory genes in the brain parenchyma and in cerebral arteries, thereby contributing to the infarct development. The present study was designed to evaluate the involvement of calcium-calmodulin-dependent protein kinase (CaMKI...

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Hoofdauteurs: Waldsee, Roya, Eftekhari, Sajedeh, Ahnstedt, Hilda, Johnson, Leif E, Edvinsson, Lars
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4039324/
https://ncbi.nlm.nih.gov/pubmed/24886705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-11-90
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