Pharmacological correction of misfolding of ABC proteins()

The endoplasmic reticulum (ER) quality control system distinguishes between correctly and incorrectly folded proteins to prevent processing of aberrantly folded conformations along the secretory pathway. Non-synonymous mutations can lead to misfolding of ABC proteins and associated disease phenotype...

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Библиографические подробности
Главные авторы: Rudashevskaya, Elena L., Stockner, Thomas, Trauner, Michael, Freissmuth, Michael, Chiba, Peter
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2014
Предметы:
Transporter Assays
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4039138/
https://ncbi.nlm.nih.gov/pubmed/25027379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ddtec.2014.03.009
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