The Continual Reassessment Method for Multiple Toxicity Grades: A Bayesian Model Selection Approach

Grade information has been considered in Yuan et al. (2007) wherein they proposed a Quasi-CRM method to incorporate the grade toxicity information in phase I trials. A potential problem with the Quasi-CRM model is that the choice of skeleton may dramatically vary the performance of the CRM model, wh...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Pan, Haitao, Zhu, Cailin, Zhang, Feng, Yuan, Ying, Zhang, Shemin, Zhang, Wenhong, Li, Chanjuan, Wang, Ling, Xia, Jielai
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038518/
https://ncbi.nlm.nih.gov/pubmed/24875783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098147
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