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The Continual Reassessment Method for Multiple Toxicity Grades: A Bayesian Model Selection Approach
Grade information has been considered in Yuan et al. (2007) wherein they proposed a Quasi-CRM method to incorporate the grade toxicity information in phase I trials. A potential problem with the Quasi-CRM model is that the choice of skeleton may dramatically vary the performance of the CRM model, wh...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4038518/ https://ncbi.nlm.nih.gov/pubmed/24875783 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098147 |
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