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In vitro supplementation with deoxynucleoside monophosphates rescues mitochondrial DNA depletion
Mitochondrial DNA depletion syndromes are a genetically heterogeneous group of often severe diseases, characterized by reduced cellular mitochondrial DNA content. Investigation of potential therapeutic strategies for mitochondrial DNA depletion syndromes will be dependent on good model systems. We h...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4038513/ https://ncbi.nlm.nih.gov/pubmed/22608879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2012.04.022 |
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