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Safety and Efficacy Assessment of Two New Leprosy Skin Test Antigens: Randomized Double Blind Clinical Study

BACKGROUND: New tools are required for the diagnosis of pre-symptomatic leprosy towards further reduction of disease burden and its associated reactions. To address this need, two new skin test antigens were developed to assess safety and efficacy in human trials. METHODS: A Phase I safety trial was...

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Bibliografische gegevens
Hoofdauteurs: Rivoire, Becky L., Groathouse, Nathan A., TerLouw, Stephen, Neupane, Kapil Dev, Ranjit, Chaman, Sapkota, Bishwa Raj, Khadge, Saraswoti, Kunwar, Chatra B., Macdonald, Murdo, Hawksworth, Rachel, Thapa, Min B., Hagge, Deanna A., Tibbals, Melinda, Smith, Carol, Dube, Tina, She, Dewei, Wolff, Mark, Zhou, Eric, Makhene, Mamodikoe, Mason, Robin, Sizemore, Christine, Brennan, Patrick J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038488/
https://ncbi.nlm.nih.gov/pubmed/24874401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002811
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