Safety and Efficacy Assessment of Two New Leprosy Skin Test Antigens: Randomized Double Blind Clinical Study

BACKGROUND: New tools are required for the diagnosis of pre-symptomatic leprosy towards further reduction of disease burden and its associated reactions. To address this need, two new skin test antigens were developed to assess safety and efficacy in human trials. METHODS: A Phase I safety trial was...

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Detalhes bibliográficos
Main Authors: Rivoire, Becky L., Groathouse, Nathan A., TerLouw, Stephen, Neupane, Kapil Dev, Ranjit, Chaman, Sapkota, Bishwa Raj, Khadge, Saraswoti, Kunwar, Chatra B., Macdonald, Murdo, Hawksworth, Rachel, Thapa, Min B., Hagge, Deanna A., Tibbals, Melinda, Smith, Carol, Dube, Tina, She, Dewei, Wolff, Mark, Zhou, Eric, Makhene, Mamodikoe, Mason, Robin, Sizemore, Christine, Brennan, Patrick J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038488/
https://ncbi.nlm.nih.gov/pubmed/24874401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002811
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