A Novel Universal Neutralizing Monoclonal Antibody against Enterovirus 71 That Targets the Highly Conserved “Knob” Region of VP3 Protein

Hand, foot and mouth disease caused by enterovirus 71(EV71) leads to the majority of neurological complications and death in young children. While putative inactivated vaccines are only now undergoing clinical trials, no specific treatment options exist yet. Ideally, EV71 specific intravenous immuno...

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Autores principales: Kiener, Tanja K., Jia, Qiang, Meng, Tao, Chow, Vincent Tak Kwong, Kwang, Jimmy
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038473/
https://ncbi.nlm.nih.gov/pubmed/24875055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002895
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