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Effective in vivo therapeutic IgG antibody against VP3 of enterovirus 71 with receptor-competing activity
Passive immunization is an effective option for treatment against hand, foot and mouth disease caused by EV71, especially with cross-neutralizing IgG monoclonal antibodies. In this study, an EV71-specific IgG2a antibody designated 5H7 was identified and characterized. 5H7 efficiently neutralizes the...
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Publicado no: | Sci Rep |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5395816/ https://ncbi.nlm.nih.gov/pubmed/28422137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep46402 |
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