Effective in vivo therapeutic IgG antibody against VP3 of enterovirus 71 with receptor-competing activity

Passive immunization is an effective option for treatment against hand, foot and mouth disease caused by EV71, especially with cross-neutralizing IgG monoclonal antibodies. In this study, an EV71-specific IgG2a antibody designated 5H7 was identified and characterized. 5H7 efficiently neutralizes the...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Jia, Qiang, Ng, Qingyong, Chin, Wenjie, Meng, Tao, Chow, Vincent Tak Kwong, Wang, Cheng-I, Kwang, Jimmy, He, Fang
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395816/
https://ncbi.nlm.nih.gov/pubmed/28422137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep46402
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